Using shRNA experiments to validate gene regulatory networks
نویسندگان
چکیده
منابع مشابه
Using shRNA experiments to validate gene regulatory networks
Quantitative validation of gene regulatory networks (GRNs) inferred from observational expression data is a difficult task usually involving time intensive and costly laboratory experiments. We were able to show that gene knock-down experiments can be used to quantitatively assess the quality of large-scale GRNs via a purely data-driven approach (Olsen et al. 2014). Our new validation framework...
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ژورنال
عنوان ژورنال: Genomics Data
سال: 2015
ISSN: 2213-5960
DOI: 10.1016/j.gdata.2015.03.011